Enhanced memory for detail in autism
Much research on autism focuses only on deficits in social cognition. But another common hallmark of autism-spectrum disorders is an enhanced memory for details, such as types of objects and their location, words from different languages, types of cars etc. (‘item’ memory)…
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Immunotherapy of Cancer
In cancer patients, immunotherapy may have quite different outcomes, curative or lethal, which so far cannot be predicted on the basis of conventional markers.
We will carry out bioinformatic analyses of publicly available microarray and RNAseq …
Drug Resistance
With the development of biologic drugs targeting intracellular pathways, such as lapatinib for breast cancer…
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Models of Neural Plasticity
Our work on basing models of neural plasticity on cellular principles continues to advance. With the help of Michael Wheeldon, B.Sc., as the current recipient of a research scholarship we anticipate two publications at the beginning of the new year. One publication will focus on outlining a new type of memory model using both horizontal Read more..
Pharmacodynamics: Problems and Pitfalls
A systematic overview of qualitative and quantitative model evaluation methods with many detailed references. This is applied and substantiated with case studies, and most interestingly, with an analysis of what can go wrong. Dynamic models are highly sensitive to uncertainties and we need to be aware of the difficulties that can arise from that. S. Read more..
